Room / building      F-182, 1. basement; Ke Karlovu 2026/5, Praha 2

Defended theses

1. Bachelor thesis: Vibrational optical activity of 3-aminoquinuclidine
2. Diploma thesis: Vibrational optical activity of nucleotides and shorter nucleic acid segments

Funding

• main investigator of project GAUK No. 298123, Study of structural polymorphism of G-quadruplexes via methods of chiroptical spectroscopy, 2023–2025

Publications

1. Spasovová, M.; Kapitán, J.; Jílek, Š.; Siddhique Para Kkadan, M.; Klener, J.; Scott Lynn Jr., N.; Kopecký Jr., V.; Baumruk, V.; Profant, V. (2024) Probing Solution Conformations of L-DOPA: Integration of Experiment and Simulation via Vibrational Optical Activity. Spectrochim Acta A Mol Biomol Spectrosc, 313, 124119. https://doi.org/10.1016/j.saa.2024.124119.
2. Kkadan, M. S. P.; Jílek, Š.; Profant, V.; Kapitán, J.; Kessler, J.; Bouř, P. (2024) Detection of Guanine Quadruplexes by Raman Optical Activity and Quantum‐Chemical Interpretation of the Spectra. Chemistry – A European Journal, 30 (70). https://doi.org/10.1002/chem.202403245.

Awards

1. Spectroscopic society of Ioannes Marcus Marci
   • 2nd place in the contest of the best diploma thesis in the spectroscopic field

2. 19^th European Conference on the Spectroscopy of Biological Molecules (ECSBM), Reims, France
   • Best student oral contribution – Raman optical activity as a potent tool for studies of mononucleotide G-quadruplexes

3. 18^th Czech – Slovak Spectroscopic Conference (CSSC), Kurdějov, Czech Republic
   • Best student oral contribution within the Microsymposium of vibrational spectroscopy – Exploring Mononucleotide G-quadruplexes through Vibrational and Chiroptical Spectroscopy

4. 34^th International Symposium on Chirality, Kyoto, Japan
   • Shimadzu poster award – Guanosine 5’-monophosphate self-assemblies: Can Raman Optical Activity decipher their complexity?